The discoveries, tragedies, and breakthroughs that shaped modern medicine

Scroll to Explore

Pre-1900s

ERA 01

Ancient Observations

The earliest recorded observations of dangerous substance combinations

Click to explore →


1906–1937

ERA 02

The Sulfanilamide Disaster

107 deaths that created the modern FDA

Click to explore →


1957–1962

ERA 03

Thalidomide

The morning sickness drug that changed drug testing forever

Click to explore →


1963

ERA 04

The Cheese Effect

How aged cheese revealed a deadly interaction hiding in plain sight

Click to explore →


1954–Present

ERA 05

The Warfarin Problem

From rat poison to life-saving blood thinner — and its deadly combinations

Click to explore →


1989

ERA 06

The Grapefruit Discovery

An accidental finding during an alcohol study that affects 85+ medications

Click to explore →


1992–1998

ERA 07

The Seldane Withdrawal

The world's best-selling antihistamine pulled for a fatal interaction

Click to explore →


1991–Present

ERA 08

Serotonin Syndrome

The underdiagnosed condition hiding inside common antidepressant combinations

Click to explore →


2000s–2010s

ERA 09

The Polypharmacy Crisis

When taking more medications became more dangerous than the diseases they treat

Click to explore →


2020s

ERA 10

AI and the Future

How artificial intelligence is transforming drug interaction detection and prevention

Click to explore →